Project Description


1366108147_nausea-and-vomitingNausea is a sensation of unease and discomfort in the upper stomach with an involuntary urge to vomit. It occasionally precedes vomiting. A person can suffer nausea without vomiting.

Nausea is a non-specific symptom, which means that it has many possible causes. Some common causes of nausea are motion sickness, dizziness, migraine, fainting, gastroenteritis (stomach infection) or food poisoning. Side effects of many medications including cancer chemotherapy, nauseants or morning sickness in early pregnancy. Nausea may also be caused by anxiety and depression.

Prescription medications taken to prevent and treat nausea are called antiemetics. The most commonly prescribed antiemetics are promethazine, metoclopramide and ondansetron.

Medical Marijuana Efficacy

The anti-nausea effects of medicinal marijuana are well known both scientifically and among users who have experienced relief from nausea and vomiting. While cannabinoids isolated from the cannabis plant also help to mitigate nausea, smoking medical marijuana provides superior treatment for vomiting when compared to THC ingested orally.

Official Research Reports

Motion sickness, stress and the endocannabinoid system (Choukèr A, Kaufmann I, Kreth S, Hauer D, Feuerecker M, Thieme D, Vogeser M, Thiel M, Schelling G, 2010)

Use of medical marijuana for treatment of severe intractable nausea after laparoscopic Roux-en-Y gastric bypass surgery. (Merriman AR, Oliak DA, 2008)

Survey of medicinal cannabis use among childbearing women: patterns of its use in pregnancy and retroactive self-assessment of its efficacy against ‘morning sickness’. (Westfall RE, Janssen PA, Lucas P, Capler R, 2006)

Prevention of nausea and vomiting following breast surgery. (Layeeque R, Siegel E, Kass R, Henry-Tillman RS, Colvert M, Mancino A, Klimberg VS, 2006)

Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac. (Söderpalm AH, Schuster A, de Wit H, 2001)

Effect of nabilone on nausea and vomiting after total abdominal hysterectomy. (Lewis IH, Campbell DN, Barrowcliffe MP, 1994)

A double-blind randomised cross-over comparison of nabilone and metoclopramide in the control of radiation-induced nausea. (Priestman SG, Priestman TJ, Canney PA, 1987)

Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-tetrahydrocannabinol. (Ekert H, Waters KD, Jurk IH, Mobilia J, Loughnan P, 1979)

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